The two Pseudomonas aeruginosa strains resistant to carbapenems were also acquired in the intensive care unit. Among the identified aerobic gram-positive bacteria, Enterococci (E. faecalis and E. faecium) were identified in 101 cases (14.5% of all aerobic isolates). Eight glycopeptide-resistant Enterococci see more were isolated (six were glycopeptide-resistant
Enterococcus faecalis isolates, and two were glycopeptide-resistant Enterococcus faecium isolates). Although Enterococci were also present in community-acquired infections, they were far more prevalent in healthcare-associated infections. The identified peritoneal isolates from both healthcare-associated and community-acquired IAIs are listed in Table 5. Table 5 Aerobic bacteria in community acquired and health-care GDC-0941 cell line associated IAIs Community-acquired IAIs Isolates n° Healthcare associated IAIs Isolates
n° P Aerobic bacteria 498 (100%) Aerobic bacteria 199 (100%) Escherichia coli 259 (52,2%) Escherichia coli 55 (27,6%) 0,0002 (Escherichia coli resistant to third generation cephalosporins) 21 (4,2%) (Escherichia coli resistant to third generation cephalosporins) 14 (7%) NS Klebsiella pneumoniae 31 (6,2%) Klebsiella pneumoniae 24 (12%) 0,0275 (Klebsiella pneumoniae resistant to third generation cephalosporins) 6 (1,2%) (Klebsiella pneumoniae resistant to third generation cephalosporins) 13 (6,5%) 0,0005 Pseudomonas 22 (4,4%) Pseudomonas 10 (5%) NS Enterococcus faecalis 37 (7,4%) Enterococcus faecalis 33 (16,6%) 0,002 Enterococcus faecium 17 (3,4%) Enterococcus faecium 14 (7%) NS 278 patients were tested for anaerobes. 83 different anaerobes were ultimately observed. The most frequently identified anaerobic pathogen was Bacteroides. 57 Bacteroides isolates were observed during the initial course of the study. Among the Bacteroides isolates, there was one Metronidazole-resistant Inositol oxygenase strain. A complete overview of the identified
anaerobic bacteria is reported in Table 6. Table 6 Anaerobic bacteria in the peritoneal fluids Anaerobes 83 Bacteroides 57 (68,7%) (Bacteroides resistant to metronidazole) 1 (1,2%) Clostridium 6 (7,2%) (Clostridium resistant to metronidazole) 1(1,2%) Others 20 (24%) Additionally, there were 45 Candida isolates identified among the 825 total isolates (4.7%). 36 were Candida albicans and 9 were Candida non albicans. Two particular candida isolates (one Candida albicans and one Candida non albicans) appeared to be fluconazole-resistant (see Table 7). Table 7 Candida isolates in the peritoneal fluids Candida 45 Candida albicans 36 (80%) (Candida albicans resistant to fluconazole) 1 (2,2%) Non albicans Candida 9 (20%) (non albicans Candida resistant to fluconazole) 1 (2,2%) The prevalence of Candida was noticeably elevated in the healthcare-associated IAI group (232 total isolates). 25 Candida isolates (10.8%) were observed in this group compared to 20 Candida isolates (3.