In summary, both participants experienced a decrease in the frequency of their binge episodes throughout the course of the intervention, and these decreases were largely maintained at the 3-month follow-up (see Table 3). The average number of binge INCB024360 supplier eating episodes per week across both participants at pretreatment was 5.7, which decreased to 2.0 per week at posttreatment, and 1.3 per week at follow-up. The improvements were particularly significant in Participant 1, who no longer met criteria for BED at posttreatment and 3-month follow-up. Similarly, improvements in body image flexibility were observed

across both participants throughout the course of study. At pretreatment, the mean body image flexibility score was 34.5. During the course of ACT intervention, the mean score was 46.7, followed by 43.0 at follow-up. The current study sought to investigate the effectiveness DNA Damage inhibitor of a 10-week ACT individual intervention for two women diagnosed with BED and offers guidance for clinicians on the use of ACT for this disorder. The average amount of weekly binge eating across both participants decreased

at posttreatment, and the reduction remained at follow-up. One participant no longer met criteria for BED at posttreatment. The other participant remained symptomatic at posttreatment and follow-up, although there was reduction of binge eating in frequency tuclazepam and the volume of food consumed during a binge at both assessment points. Increases in body image flexibility were observed in both participants throughout the course of study, and improvements in body image flexibility corresponded to reductions in disordered eating. The present ACT intervention was also consistent with literature on emotion regulation and its role in disordered eating, which suggests that binge eating functions as a method of attempting to escape or distract oneself from difficult thoughts and emotions (Hayaki, 2009 and Polivy and Herman, 2002). In practice, various ACT techniques

were used to undermine the rigid use of these regulation strategies so that they did not interfere with daily functioning, while also helping to shift participants’ focus to pursuing values-consistent living. At follow-up, both participants reported that they enjoyed and benefited from focusing on valued living rather than binge eating exclusively. They found it useful to incorporate skills for broader functioning in order to undermine maladaptive regulation strategies. With regard to experiential exercises, both participants reported that the exercises were helpful in learning how to relate to negative internal experiences in more adaptive ways. They also suggested that they would have liked to engage in more of these types of exercises throughout treatment.