4 m/s, p = 0.0048).
Conclusion: The proposed CMR protocol quantifies multiple aspects of vascular reactivity and represents an initial step toward development of a potential tool for evaluating AG-014699 in vivo interventions, extrapolating clinical outcomes and predicting functional endpoints based on quantitative parameters.”
“Polyphenol extracts from industrial sour cherry pomaces were characterized on polyphenol composition, antioxidant capacity and antimicrobial activity. Extracts of pomace were purified and freeze-dried. Preparations were characterized by high polyphenol contents including anthocyanins, hydroxycinnamic acids and flavonoids, selected were characterized by high flavanol content and high antioxidant capacity. The antimicrobial effect
of sour cherry polyphenol extracts was tested against Salmonella, Escherichia coil 0157:H7 and Listeria spp. The bacteriostatic effect was tested by growing the strains in a liquid medium containing the extracts, the bactericide effect was assayed by putting the strains in direct contact in an aqueous suspension of the extract, simulating the disinfection process in the fresh-cut industry. Two of the sour cherry extracts tested reduced the growth of Salmonella and E. coli O157:H7 at concentrations higher than 2500 mu g/mL, and inhibited Listeria spp. growth. (C) 2013 Elsevier B.V. All rights reserved.”
“Objectives:
To study the construct validity and Rocilinostat reliability of a novel endovascular global rating scale, Structured Assessment of endoVascular Expertise (SAVE). Design: A Clinical, experimental study.
Design: A Clinical, experimental study.
Materials: Twenty physicians with endovascular experiences ranging from complete novices to highly experienced operators performed a video-recorded simulated contra-lateral iliac-artery-stenting procedure. The virtual-patient case was a novel technically challenging procedure presenting the distal arteries below the knee.
Methods: Three experts assessed the performances blinded to operator identity. Validity was analysed by correlating
experience with performance results. Reliability was analysed according to generalisability theory.
Results: The mean score on the 29 items of the SAVE scale correlated well with clinical experience (R = 0.84, P < 0.01) and was found discriminative even among the more experienced participants having performed up to 500 endovascular PERK inhibitor procedures in total. Only the most experienced participants (> 5000 procedures) obtained maximum scores. The inter-rater reliability was high (G = 0.94 and G = 0.95). The procedure time (median 69 min, range 32-86) correlated moderately with clinical experience (R = -0.53, P < 0.05), whereas the fluoroscopy time and amount of contrast fluid did not correlate.
Conclusions: The construct validity and reliability of assessment with the SAVE scale was high when applied to performances in a simulation setting with advanced realism. No ceiling effect was present in the assessment situation.