To test MAPK inhibitor differences in the prevalence of complaints between surgeons and other hospital physicians, four body regions were

formed: the neck region (neck and upper A-769662 molecular weight back), the lower back region, the arm region (shoulder, elbow, forearm and wrist) and the leg region (hip, knee, leg and ankle). The original response categories for physical work ability were recoded into two categories (once a month or less and several times a month or more). A frequency count and a Chi-square test were performed to test for differences. All analyses were performed using SPSS 17.0 for Windows. Results All 126 of the planned observations were executed. Based on the conclusion from the explorative interviews that the tasks and activities of medical residents during a working day were the most representative of tasks and activities for a general working day, observations were performed

with medical residents. From the 458 questionnaires (response rate 51 %) that were returned, a total of 395 questionnaires could be used for analysis. Some questionnaires were filled out incompletely, while a few others were filled out by medical doctors that performed non-clinical functions and were therefore considered not to be representative. Most surgeons (55 %) were males, while most of the other hospital physicians (55 %) were females (Table 1). Table 1 Overview of the demographic characteristics of the questionnaire study population   Surgeons (n = 100) Hospital physicians (n = 295) Total (n = 395) % (n) %

(n) % (n) Male 55 (55) 45 (131) 47 (186) Female 45 (45) 55 (163) 53 (208) Medical doctor 59 (59) 51 (151) 53 (210) Medical resident 41 (41) 49 (144) 47 (185) this website   Mean (SD) Mean (SD) CYC202 Mean (SD) Age (years) 41 (10.8) 40 (9.8) 41 (10.0) Physical exposure Table 2 gives an overview of the mean duration and frequency of activities and body postures. During an average working day, surgeons spent an equal amount of time sitting and standing (approximately 4 h each), whereas other hospital physicians spent more time sitting than standing (6 vs. 3 h, respectively). Surgeons make fine repetitive movements for a significantly longer time (80 min) compared with other hospital physicians (3 min), while the latter group works significantly longer on a computer (104 min) compared with surgeons (73 min). Both groups of physicians frequently perform cervical flexions or rotations, while the mean frequency of the other body postures is relatively low. Table 2 Duration and frequency of activities and body postures, and a comparison between surgeons and other hospital physicians   Surgeons (n = 44) Hospital physicians (n = 82) U a p Mean 95 % CI Mean 95 % CI Duration activities (min) Sitting* 279 230–328 351 315–386 1,342 .018 Standing* 267 217–318 187 154–219 1,248 .004 Fine repetitive movements* 80 38–123 3 0–7 1,209 <.001 Working on a computer* 73 48–98 104 85–123 1,349 .019 Walking 45 36–54 46 41–51 1,669 .488 Duration body postures (min) Cervical flexion (>25°) 119 82–157 71 61–82 1,505 .