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By integrating DNA methylation and gene expression profiles and application of bioinformatics Ans Courts, our analysis suggested the way St significant Requirements tumor suppressive functions hypermethylation and upregulation of tumor promotion stunt by hypomethylation. These experimental methods and the calculation can be very useful to identify key mediators of chemotherapy resistance as potential biomarkers or therapeutic targets. Ver MODIFIED methylation patterns obtained with Hter activity T or are assigned in the DNA methyltransferases, the family of enzymes that catalyze the transfer of a methyl group of DNA, using S-adenosylmethionine as a methyl donor. Although the relationship between the hypermethylation of genes and VER DNMT RNA levels MODIFIED in ovarian cancer cells is not easy, was significant increase of DNMTs in cisplatin resistance acquired observed ovarian cancer, suggesting that the aberrant methylation patterns can be obtained with a Hten be associated