6%) consists of stem cells, which are not originated from primordial germ cells. Absence of Oct-4

gene expression in more than half of the cases means probably the end of the productive journey of these cells, towards the oocyte.”
“Background: Bystander CPR rates are lowest at home, where 85% of out-of-hospital cardiac arrests occur. Z-VAD-FMK clinical trial We sought to identify barriers and facilitators to CPR training and performing CPR among older individuals most likely to witness cardiac arrest.

Methods: We selected independent-living Canadians aged >= 55 using random-digit-dial telephone calls. Respondents were randomly assigned to answer 1 of 2 surveys eliciting barriers and facilitators potentially influencing either CPR training or performance. We developed survey instruments using HSP990 the Theory of Planned Behavior, measuring salient attitudes, social influences, and control beliefs.

Results: Demographics for the 412 respondents (76.4% national response rate): Mean age 66, 58.7% female, 54.9% married, 58.0% CPR trained (half >10 years ago). Mean intentions to take CPR training in the next 6 months or to perform CPR on a victim were relatively high (3.6 and 4.1 out of 5). Attitudinal beliefs were most predictive of respondents’ intentions to receive training or perform CPR (Adjusted

OR; 95% CI were 1.81; 1.41-2.32 and 1.63; 1.26-2.04 respectively). Respondents who believed CPR could save a life, were employed, and had Tyrosine Kinase Inhibitor Library seen CPR advertised had the highest intention to receive CPR training. Those who believed CPR should be initiated before EMS arrival, were proactive in a group, and felt confident in their CPR skills had the highest intention to perform CPR.

Interpretation: Attitudinal beliefs were most predictive of respondents’ intention to complete CPR training or perform CPR on a real victim. Behavioral change techniques targeting these specific beliefs are most likely to make an impact. (C)

2013 Elsevier Ireland Ltd. All rights reserved.”
“Exposure to cadmium has been established to be carcinogenic for humans by the International Agency for Research on Cancer, but this is mainly based on studies with occupational exposures. The substantial 100 year long emission of cadmium by three zinc smelters in the Kempen area across the Dutch-Belgian border might have affected the incidence of cancer in this region. Following a study of increased risks of lung cancer due to cadmium emission (hazard ratio was 4.2 for high vs. low cadmium exposure areas in that study), we used data from the three regional population-based cancer registries, covering an area with 2.9 million inhabitants. Analyses of observed incidence were carried out for all cancers and cancer of the lung, kidney, bladder, prostate, testis, and breast separately.