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Pseudomonas aeruginosa induces localized immunosuppression during pneumonia. Infect Immun 2008, 76:4414–4421.CrossRefPubMed Orotidine 5′-phosphate decarboxylase Authors’ contributions KS carried out most of experimental works, and drafted the manuscript. SI performed the genetic studies. NK improved some of the experimental procedures. YG provided the draft genome sequence information. MO conceived the study and co-wrote the manuscript with HW. All authors have read and 4SC-202 approved the final manuscript.”
“Background The commensal human microbiome is estimated to outnumber the amount of human body cells by a factor of ten [1]. These complex microbial communities are normal residents of the skin, the oral cavity, vaginal and intestinal mucosa and carry a broad range of functions indispensable for the wellbeing of the host [2]. Usually we only become aware of their presence when the balance between the microbiota and the host is lost, and disease is manifest.