case age sex Cirrhosis CT triple phase MRI Histology Art E Ven W Size (cm) Art E Ven W 1 = yes, 0 = no, x = not done, E = enhancement,

W = wash out, R = regenerative, corr dx = correct diagnosis Comparing the characteristics of these cases with the group of correctly diagnosed HCC using Fisher’s exact test or t test, (only the age mean reached statistical significance with age 63.88 vs. 51.20, p = 0.025). Only 2 of 5 patients with a false diagnosis showed typical radiological features of an HCC. In the group with a correct diagnosis of HCC, application of the AASLD guidelines would have resulted in liver biopsy for 26 of 50 patients with atypical imaging features. Conclusion: 1) A false

diagnosis of HCC was 9%. 2) A younger age was the only statistically significant patient characteristic I-BET-762 ic50 associated with a false diagnosis of HCC. 3) Following AASLD guidelines liver biopsies could have prevented unnecessary hepatic resection in 2 patients with atypical imaging features, but would have resulted in unnecessary biopsies for 26 patients with correctly diagnosed HCC. TM GOODSALL,1 M MENON,2,3 S BOLLIPO,1,3 JK FERGUSON2,3,4 1Department of Gastroenterology, John Hunter Hospital, Newcastle, Australia, 2Department of Microbiology, Pathology North-Hunter, Newcastle, Australia, 3Faculty of Health and Medicine, The University of Newcastle,

Newcastle, Australia, 4School of Rural Medicine, Selleck Epigenetics Compound Library University of New England, Armidale, Australia Introduction: Patients with cirrhosis and diuretic resistant ascites may require regular elective therapeutic abdominal paracentesis, which can be performed in an ambulatory setting. International ascites management guidelines recommend routine bedside inoculation of blood culture bottles for all paracentesis procedures as an adjunct to cell count to exclude spontaneous bacterial peritonitis (SBP); this recommendation is based on cohort MCE公司 studies of patients selected for clinical features of SBP and/or neutrocytic ascites (Level 2a).1,2 The benefit of blood culture bottle inoculation when performing therapeutic paracentesis of otherwise well patients in an ambulatory setting has not previously been investigated. Methods: Data for all ascitic fluid samples received in our health care network over a twelve month period was extracted and de-identified. Samples were designated “inpatient” if collected during an admission to the emergency department or wards and “ambulatory” if collected at a gastroenterology clinic or day procedure unit. A positive result was defined as the growth of an organism in a blood culture bottle. For every positive result the medical records were reviewed for documentation of the relevant encounter.