N withdraw and not progesterone erismodegib increased Ht 28 days control was very effective in the treatment of HMB and was associated with a high overall response rate in terms of treatment success and the proportion of women with MBL linked below 80 ml or 50% of MBL. The benefits were obtained with E2V/DNG were evident by the withdrawal bleed at the end of the first treatment cycle and were kept with other small improvements over the course of treatment. Acknowledgements This study was funded by Bayer HealthCare Pharmaceuticals, Berlin, Germany, the manufacturer of E2V/DNG. Medical writing services may need during the preparation of this manuscript were provided by Amy Evans. A written Einverst Ndniserkl Tion was to study by all participants before inclusion, provided tion in accordance with the Helsinki explanation:. Each participant had the right to withdraw from the study at any time without notice for any reason. The study medication study medication was provided to participants in three blisters of 28 tablets each, with maps of the available reserves in the study center. Participants took one tablet in the mouth t Possible for up to 72 days. To maintain blinding, packaging and tablet formulations, independent Ngig on the dose, were identical in appearance. Participants were encouraged to study medication at the same time each day. Missed tablet as soon as you remember, unless it took more than 12 hours since the standard time of the contribution had passed, in this case, the missed tablet has not been taken, the participant continues to be a tablet at the usual time to take on the n next day. Participants were excluded from the analysis if they are less than 95% of the planned dose, or if they missed pill for 2 consecutive days or l Longer than 2 days after 36 days of treatment. Did the treatment compliance of the participants was that the number of tablets taken and recorded at the time of taking the tablet in the papers, documents, and also by the return of blister cards, including leftover pills at the end of the study. Pharmacodynamic Ma took Ovarian activity t was based with the scoring system Hoogland, 23 on the diameter of the gr Th follicle as the structure and the serum concentrations of Estradiol and progesterone. Distinguished by the combination of data on the pattern of growth hormone measurement with FLSS between cystic structures and stages of ovarian activity t. Hoogland Score was used in previous clinical studies, the activity at t the Eierst skirts w Were measured during the 26 COC.24 Hoogland scores for the pretreatment and time for two different ZEITR Ume of observation w Recorded during the treatment. TVU was performed at each study visit to both Eierst skirts and the building Rmutter to investigate. The gr-Run FSL and the diameter was determined as the average L Calculated longitudinal and transverse diameter. Endometrial thickness was measured in the sagittal section. Blood samples were collected to determine at each visit in times of pretreatment and treatment to serum E2, progesterone, FSH, LH and concentrations. Testing the LH surge was also carried out by the participants at home in the morning urine using a digital ovulation test in the pretreatment and follow-up period until ovulation was best CONFIRMS. The Insler score, a semiquantitative evaluation of the building Rmutterhalses and the amount and type of cervical mucus, WA.